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Plasticité chez l’homme sain et cérébro-lésé etudiée avec l’imagerie
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"Imaging neuroscience describes the functional organization of human brain at the level of large neuronal groupings, networks and systems. A systems level of description addresses how integrated brain functions are embodied in the physical structure of the brain. Magnetic resonance imaging (MRI) is now the modality of choice in structural and functional imaging neuroscience. The analysis of structural and functional brain images can nowadays be carried out automatically using statistical parametric mapping (SPM). The resultant ability to perform clinical-functional-anatomical correlative studies in life with complete objectivity and unparalleled sensitivity is providing powerful new opportunities for the study of brain pathology and plasticity. One of the most exciting and dramatic observations to come from human brain mapping with a wide range of structural and functional techniques is the dynamic plasticity of function in the brains of patients with strokes. Recent activation studies have provided interesting information about the brains capacity to reorganise after such injury and in association with practice and learning that constitute the bedrock of rehabilitation. Though presently in the realm of basic physiology, the study of brain plasticity and its modulation by drugs and other therapies indicates a novel approach to the rehabilitation of stroke damaged adults. Brain maps must be viewed as dynamic, changing with development, disease progression and in the recovery of function after acute injury. The dynamic plasticity of functional brain maps provides an exciting opportunity to study these processes.  "

Richard Frackowiak
Université de Lausanne / Centre Hospitalier Universitaire Vaudois
Directeur du service neurologie

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Professeur à l’Université de Lausanne, Suisse, Richard Frackowiak est directeur du département des neurosciences cliniques et médecin-chef du service de neurologie au Centre Hospitalier Universitaire Vaudois (CHUV).

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Dernière mise à jour : 16/02/2012