Exposé de Mart Krupovic (Archaeal Virology Unit, Dpt of Microbiology, Institut Pasteur) dans le cadre du Séminaire Cavaillès (Histoire et Philosophie du vivant) organisé par la République des Savoirs à l'ENS-PSL.
Viruses of archaea represent one of the most enigmatic parts of the virosphere. Most of the characterized archaeal viruses infect extremophilic hosts and display remarkable diversity of virion morphotypes, many of which have never been observed among bacteriophages or viruses of eukaryotes. However, recent environmental studies have shown that archaeal viruses are widespread also in moderate soil and marine ecosystems, where they play an important ecological role by influencing the turnover of microbial communities, with a global impact on the carbon and nitrogen cycles. During the seminar, I will present the recent advances in our understanding of the genomic and morphological diversity of archaeal viruses and the molecular biology of their life cycles and virus-host interactions. I will highlight some of the molecular adaptations underlying the stability of archaeal viruses in extremely hot acidic environments. Finally, I will examine the potential origins and evolution of archaeal viruses and discuss their place in the global virosphere.
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Cursus :
Mart Krupovic est virologiste et microbiogiste, responsable de la structure "Virologie des Archées" à l'Institut Pasteur.
Ses recherches portent principalement sur l'origine et l'évolution de divers groupes de virus bactériens, archéens et eucaryotes, ainsi que sur les relations entre les virus et d'autres types d'éléments génétiques mobiles, notamment les plasmides et les transposons. Il utilise des approches théoriques, computationnelles et expérimentales pour aborder ces questions.
Cliquer ICI pour fermerDernière mise à jour : 27/06/2024